Advances in Cancer Research, Vol. 107 by George F. Vande Woude

By George F. Vande Woude

Advances in melanoma learn offers necessary details at the intriguing and fast-moving box of melanoma examine. right here, once more, remarkable and unique studies are provided on various issues

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29, 416–424. Liyanage, U. , Moore, T. , Joo, H. , Drebin, J. , Strasberg, S. , Eberlein, T. , Goedegebuure, P. , and Linehan, D. C. (2002). Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J. Immunol. 169, 2756–2761. Lopez, D. , and Adkins, B. (2002). Influence of breast cancer on thymic function in mice. J. Mammary Gland Biol. Neoplasia 7, 191–199. Lutsiak, M. , Semnani, R. , Kashmiri, S. , and Sabzevari, H.

Rather, we focus on the potential roles of leptin and adiponectin, as well as two hereditary cancer genes, which encode proteins that provide a regulatory link between the lipid and biosynthetic pathways. We have included discussions on the clear-cell phenotype, transcriptional regulation of lipid biosynthesis, and also VHL function, since this is the most frequently mutated gene 42 Harry A. Drabkin and Robert M. Gemmill in both hereditary and spontaneous RCC. Together, these data make a compelling case that alterations in lipid homeostasis play a role in RCC development.

Van den Enden-Vieveen, M. , and de Leeuw, A. M. (1988). Animal model of human disease. Multiple myeloma. Am. J. Pathol. 132, 593–597. , Brown, R. , and Joshua, D. E. (2003). T cells in myeloma. Hematol. Oncol. 21, 33–42. Rajkumar, S. , Gertz, M. , Lacy, M. , Greipp, P. , Lust, J. , Kyle, R. , and Witzig, T. E. (2002). Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma. J. Clin. Oncol. 20, 4319–4323. , Della Cuna, G. , and Lemoli, R. M. (2002). Dendritic cells are functionally defective in multiple myeloma: The role of interleukin-6.

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