Application of Hyperthermia in the Treatment of Cancer by S. B. Field (auth.), Dr. med. Dipl. biochem. Rolf D. Issels,

By S. B. Field (auth.), Dr. med. Dipl. biochem. Rolf D. Issels, Prof. Dr. med. Wolfgang Wilmanns (eds.)

Physicians, biologists and physicists current their contemporary paintings within the box of hyperthermia in regards to either its software and its mix with radiation and chemotherapy. present technical chances, medical administration and significant features of its use for superficial and deep-seated tumors are mentioned. the most subject matters mentioned are: adjustments of metabolism and microcirculation lower than warmth stipulations, the organic interplay of warmth with X-rays and a number of other chemotherapeutic brokers, and the newest scientific information from diversified associations at the mixed software within the therapy of cancer.

Show description

Read Online or Download Application of Hyperthermia in the Treatment of Cancer PDF

Similar cancer books

Cancer: Basic Science and Clinical Aspects

This ahead having a look melanoma biology ebook appeals to a breathtaking viewers. Introductory chapters that supply the molecular, mobile, and genetic info had to understand the fabric of the next chapters convey unprepared scholars up to the mark for the remainder of the e-book and function an invaluable refresher for people with past biology historical past.


This consultant is for breast melanoma sufferers, their spouses and youngsters, and their households, co-workers, and neighbors. the writer hopes to respond to the sensible, lifestyle questions that each breast melanoma sufferer or family member has. The booklet presents info, concepts, information, and notion for every thing from that first biopsy to the five-year check-up.

Gastrointestinal Cancer (M.D. Anderson Cancer Care Series)

Gastrointestinal melanoma contains melanoma of the digestive method - the esophagus, colon, rectum, anus, liver, pancreas, and different digestive organs. Taken as a complete, there are an expected 250,600 new circumstances within the US. Colon and rectum melanoma is the 3rd top reason for melanoma and melanoma deaths within the US.

Camptothecins in Cancer Therapy (Cancer Drug Discovery and Development)

A severe assessment our present realizing of camptothecins, their shortcomings, and of the probabilities for bettering their scientific functionality. The authors speak about new camptothecin analog improvement, drug supply matters for optimizing their anticancer task, and their strength use in a number of diverse cancers.

Extra info for Application of Hyperthermia in the Treatment of Cancer

Sample text

Discussion As shown by previous studies (Kreisl and Lengfelder 1984; Betts et al. 1983; Fink and Lengfelder 1987) degradation of HA is an appropriate parameter to investigate the production and reactivity of OR" -like species as well as the formation of ferryl (Fe2+0) and/or perferryl (Fe2+02 ~ FeHOn species. Our present results demonstrate that the potential of various thiols in promoting the generation of highly oxidizing species in the presence of chelated ferric ions greatly depends on the type and effective concentration of thiol applied, as well as on the prevailing temperature.

Taylor and Francis, London, pp 173-176 Lammertsma AA, Wise RJS, Cos TCS, Thomas DGT, Jones T (1985) Measurement of blood flow, oxygen utilisation, oxygen extraction ratio, and fractional blood volume in human brain tumours and surrounding oedematous tissue. Br J Radiol 58: 725 - 734 Lee SY, Song CW, Levitt SH (1985) Change in fibrinogen uptake in tumors by hyperthermia. Eur J Cancer Clin Oncol12: 1507-1513 Lee SY, Ryu K, Kang MS, Song CW (1986) Effect of hyperthermia on the lactic acid and fJ-hydroxybutyric acid contect in tumor.

In this instance the circulation was evaluated by means of a laser-doppler fluxmeter, giving an indication of the total erythrocyte flux in the tumour. As can be seen (in Fig. 2, when the temperature is increased, the tumour blood flow first increases, then maintains a plateau for some time but, under the conditions of the continuous temperature increase, the flow index again starts to rise. Then, at a given heat dose, the circulation collapses, and even when the temperature is not increased further a complete vascular stasis develops.

Download PDF sample

Rated 4.69 of 5 – based on 25 votes