B Vitamins and Folate: Chemistry, Analysis, Function and by Victor R Preedy, Hideyuki Hayashi, Bernard Do, M H Ahmed,
By Victor R Preedy, Hideyuki Hayashi, Bernard Do, M H Ahmed, Lucien Bettendorff, K Shibata, T Fukuwatari, Dorla L Lildballe, T Yagi, Micheal Rychlik, C Sanchez-Moreno, R Agarwal, Faruk Ahmed, John R Guyton, F Bamonti, R Prakash, Jutta Dierkes, C Antoniades,
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Additional info for B Vitamins and Folate: Chemistry, Analysis, Function and Effects
The importance of individual amino acids in metabolism; observations on the eﬀect of adding tryptophan to a dietary in which zein is the sole nitrogenous constituent. Journal of Physiology. 35: 88–102. , 1936. Synthesis of Vitamin B1. Journal of the American Chemical Society. 58: 1504–1505. H. , 1938. Pantothenic acid. II. Its concentration and puriﬁcation from liver. Journal of the American Chemical Society. 60: 2719–2723. , 1931. Treatment of pernicious anaemia of pregnancy and tropical anaemia.
While developing a microbiological assay system for pyridoxine, Snell noticed that the content of ‘pyridoxine’ in rat tissues as determined by growth of Streptococcus faecalis was several thousand times higher than those obtained by yeast growth, rat growth or colorimetric methods. Another important ﬁnding was that when media supplemented with pyridoxine was heat-sterilized, progressively smaller amounts of pyridoxine were required by S. faecalis as the autoclave period was increased. Snell proposed that a substance, which he called ‘pseudopyridoxine’, was formed from pyridoxine by autoclaving and that S.
Although he never thought that citrus juice is the only solution to scurvy, the surgeons of the Royal Navy were by experience convinced of the eﬃcacy of citrus juice even if the reason was unknown. In the early 1880s, the Surgeon General of the Imperial Japanese Navy, Kanehiro Takagi, noticed that beriberi was common among crews and lower rank oﬃcers but not among oﬃcers who ate a Westernstyle diet. He considered that the low-protein diet was the cause of beriberi and performed an experiment in 1884 in which crews of a battleship were given bread and meat during a nine-month mission.