Breast Cancer by J. Chamberlain (auth.), Barth Hoogstraten, Ian Burn, H.

By J. Chamberlain (auth.), Barth Hoogstraten, Ian Burn, H. Julian G. Bloom (eds.)

This sequence at the therapy of melanoma is subsidized through the UICC. The editors and authors suppose strongly that extra standar­ dization in melanoma remedy is required on a global foundation. This, after all, is simply attainable if specialists from all international locations join a joint coverage of constructing their remedy designs to be had 'to training oncologists world wide. present therapy of melanoma discusses all of the gear and techniques now in use in melanoma remedy. It covers every kind of melanoma, therefore delivering the reader with entire infor­ mation on melanoma administration. In fresh a long time there was an important enhance­ ment within the remedy of melanoma, and there's wish for even fur­ ther luck during this struggle. we're confident that this sequence might help us to make a concerted reaction to the problem of can­ cer. UICC remedy and Rehabilitation Programme Ismail Elsebai Chairman 1988 IX Preface With a topic as advanced and delicate as breast melanoma, the idea that of manufacturing a e-book which displays all opinion at the subject is daunting.

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Extra resources for Breast Cancer

Sample text

In another series of 10 cases of carcinomas with bone and cartilage, the patients' ages ranged from 16-65 years. In the latter series the disease appeared to be aggressive, as 6 of the 10 patients died of their tumors. Carcinoma with Pseudosarcomatous Metaplasia These are invasive carcinomas with a highly cellular and anaplastic spindle-cell component, areas of myxoid or fibromyxoid change, mature and immature bone or cartilage, and multinucleated giant cells. Light and electron microscopic examinations have suggested that these undifferentiated "mesenchymal" elements may be derived from the epithelial cells.

The latest WHO classification of breast tumors has a separate category for "invasive ductal carcinoma with a predominant intraductal component," and suggests using this category for tumors in which the intraductal elements constitute at least 80% of the tumor. When most of these intraductal elements are of the comedo type, which is not unusual, the tumor is sometimes referred to as invasive or infiltrating comedo carcinoma. Rarely, an invasive ductal carcinoma may contain small areas of squamous metaplasia which may be associated with an area oftumor necrosis nearby.

5%. As in female patients, the prognosis is related to the stage of the disease. The overall 5-, 10-, and 15-year survival rates have been estimated as 52%-54%, 38% --40%, and 36%, respectively. In one series, no patients with in situ carcinoma died of the disease, while patients with invasive tumors had a lO-year survival rate of 79% when their axillary lymph nodes were not involved by the disease, and 11 % when positive nodes were present. The findings in the latter group were lower than in a comparable group of female patients.

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