Breast Cancer (M.D. Anderson Cancer Care Series) by Kelly K. Hunt, Geoffrey L. Robb, Eric A. Strom, Naoto T.
By Kelly K. Hunt, Geoffrey L. Robb, Eric A. Strom, Naoto T. Ueno, J. Mendelsohn
Now during this, its moment version, this totally revised medical guidebook is a vital source for the practitioner, permitting quickly, authoritative entry to the newest and top in multimodality treatments. issues lined during this quantity comprise every little thing from screening for early detection of breast melanoma, via diagnostic radiology and ultrasonography, to post-treatment rehabilitation, symptom administration and caliber of existence. new chapters on molecular prognostic and predictive markers, and sexuality and fertility concerns in girls with breast melanoma, were further. this can be the seventh quantity within the M.D. Anderson melanoma Care sequence, that includes the simplest ordinary therapy protocols from the specialists at M.D. Anderson melanoma heart.
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Extra resources for Breast Cancer (M.D. Anderson Cancer Care Series)
These risks were present for all women in the trial but were increased only in women over the age of 50 years. Common side effects reported included bothersome hot flashes and bothersome vaginal discharge. Tamoxifen was not associated with weight gain or depression. , 2002). The Italian and Royal Marsden trials showed no benefit of tamoxifen over placebo in terms of reducing the incidence of breast cancer. , lower risk) and trial design. The IBIS-1 trial showed a 33% reduction in the incidence of breast cancer with tamoxifen, confirming the breast cancer risk reduction benefit that was seen in the BCPT.
Both drugs reduced the risk of breast cancer by about 50%. While tamoxifen has been shown to reduce the incidence of LCIS and DCIS, raloxifene did not have an effect on the incidence of these Table 2–6. ) No. 99) cataract surgery Abbreviation: CI, confidence interval. a Among women not diagnosed with uterine cancer. B. Bevers diseases. , 2004). In STAR, the incidence of bone fractures was equivalent in the tamoxifene and raloxifene groups. As previously noted, raloxifene is approved by the Food and Drug Administration for the prevention and treatment of osteoporosis.
Hot flashes are more common among women near the age of menopause and women who have just discontinued estrogen replacement therapy, but hot flashes can occur in women of any age. Nonhormonal management of hot flashes can involve vitamin E, evening primrose oil, or other over-the-counter agents or some prescription medications such as venlafaxine (Effexor), gabapentin (Neurontin), or clonidine. , Astroglide, Replens). Estrogen creams should be avoided because of the sustained systemic absorption seen with such preparations.