Cerebellar Modules, Molecules, Morphology and Function by N M Gerrits

By N M Gerrits

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Extra resources for Cerebellar Modules, Molecules, Morphology and Function

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His contributions to the understanding of the morphological heterogeneity of the cerebellum are now classics in the field. What he has accomplished with basic staining methods complemented by modem neuroanatomical methods has demonstrated once again the incredible power of keen observation by a knowledgeable individual. His contributions are seminal to our current thinking about cerebellar organization. , have attested to the validity of his observations and the interpretations he ascribed to those observations.

In the cerebellum of the wild-type mice and also the caudal cerebellum of the PLCI34 mutant mice, regression of CF innervation appears to continue during the third postnatal week, and the CF innervation pattern observed in adult mice is established by P21. Thus, the distributions of PCs at P15-P21 in the wild-type cerebellum and the caudal region of the PLC[34 mutant cerebellum (Fig. 01, ×2 test). By contrast, PCs at P15-P21 in the rostral cerebellum of PLC[34 mutant mice (Fig. 05, X2 test) as those at P35-P55 (Fig.

G-K) Bright-field micrographs taken from the sites indicated in cerebellar sections A-C. Asterisks indicate cell bodies of PCs that displayed metachromatic color changes into purple by counterstaJning with toluidine blue. , 1998). 44 0 o 0 ~ ~ O 0 0 0 0 ~ I',- ~,0 ~t~ ~ " __ 0 ~0 0 0 (',,I ~ 0 0 0 O~ ~ ~. ~,~ -=-- ~ _. ~. ~ ' ~ E . ~ ~ ~ l l l . ,~ 0,,I ~ ~ ~ ~-~ ~~ {~~~s, . ~ <, = ~ J 0 ;'~ -~. -~ SlleO ,~o~ e q w n u ~,ueo~ed ~ I~ U ~ ~. ,,e' ~ - .. o o"~ ~:~,"~ ,~ ~ ~I ,'=' ~~ . ~o~ ~. o ~ ~ ~" ~"~ ~-" ~ "~'~ I~'=~ r~ ~~ ~= ~~ ~ .

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