Drug Resistance in Cancer Therapy by Robert C. Young (auth.), Robert F. Ozols M.D., Ph.D. (eds.)

By Robert C. Young (auth.), Robert F. Ozols M.D., Ph.D. (eds.)

Where do you start to seem for a up to date, authoritative article at the analysis or administration of a specific malignancy? The few basic oncology textbooks are typically old-fashioned. unmarried papers in really good journals are informative yet seldom accomplished; those are extra usually initial experiences on a really restricted variety of sufferers. definite basic journals often submit stable in-depth reports of melanoma themes, and released symposium lectures are frequently the easiest overviews on hand. Unfor­ tunately, those stories and supplementations seem sporadically, and the reader can by no means determine whilst a subject of specified curiosity should be lined. melanoma remedy and study is a sequence of authoritative volumes that goal to fulfill this want. it really is an try and determine a severe mass of oncology literature overlaying almost all oncology issues, revised often to maintain the insurance modern, simply to be had on a unmarried library shelf or by way of a unmarried own subscription. we now have approached the matter within the following type: first, through dividing the oncology literature into particular subdivisions resembling lung can­ cer, genitourinary melanoma, and pediatric oncology; moment, through asking emi­ nent specialists in every one of those parts to edit a quantity at the particular subject on an annual or biannual foundation. every one subject and tumor sort is roofed in a quantity showing often and predictably, discussing present prognosis, staging, markers, all types of therapy modalities, uncomplicated biology, and more.

Show description

Read or Download Drug Resistance in Cancer Therapy PDF

Similar cancer books

Cancer: Basic Science and Clinical Aspects

This ahead taking a look melanoma biology publication appeals to a panoramic viewers. Introductory chapters that supply the molecular, mobile, and genetic details had to understand the fabric of the next chapters deliver unprepared scholars on top of things for the remainder of the booklet and function an invaluable refresher for people with earlier biology history.

THE COMPLETE IDIOT'S GUIDE TO LIVING WITH BREAST CANCER

This advisor is for breast melanoma sufferers, their spouses and youngsters, and their households, co-workers, and associates. the writer hopes to respond to the sensible, lifestyle questions that each breast melanoma sufferer or friend has. The booklet presents info, concepts, suggestions, and notion for every thing from that first biopsy to the five-year check-up.

Gastrointestinal Cancer (M.D. Anderson Cancer Care Series)

Gastrointestinal melanoma contains melanoma of the digestive method - the esophagus, colon, rectum, anus, liver, pancreas, and different digestive organs. Taken as an entire, there are an predicted 250,600 new situations within the US. Colon and rectum melanoma is the 3rd top reason behind melanoma and melanoma deaths within the US.

Camptothecins in Cancer Therapy (Cancer Drug Discovery and Development)

A serious overview our present figuring out of camptothecins, their shortcomings, and of the chances for bettering their medical functionality. The authors speak about new camptothecin analog improvement, drug supply matters for optimizing their anticancer job, and their strength use in numerous assorted cancers.

Additional info for Drug Resistance in Cancer Therapy

Sample text

1982), Long Term Survival with Gynecological Cancer. In Prolonged Arrest of Cancer; ed. , John Wiley and Sons, New York. 27-58. H. and Coldman, AJ. A model for tumor response to chemotherapy: An integration of the stem cell and somatic mutation hypotheses. Cancer Invest. 3(6):553-564. H. and Ng, V. (1983). The effect of Cellular differentiation on the development of permanent drug resistance. Math. Biosciences 74:177-198. , Schabel. , Jr. S. (1964). Experimental evaluation of potential anticancer agents XII on the criteria and kinetics associated with Curability of experimental leukemia.

Unstable methotrexate resistance in human small-cell carcinoma associated with double minute chromosomes. New Eng. 1. Med. 308:199-202. 39. , Dower. J. T. (1984). Gene amplification in a leukemic patient treated with methotrexate. 1. Clin. Oncol. 2:2-7. 40. C. T. (1984). Cytologic evidence for gene amplification in methotrexate-resistant cells obtained from a patient with ovarian adenocarcinoma. 1. Clin. Oncol. 2:8-15. 4l. , Rivest. , Portlock. • Duffy. T. and Bertino, 1. (1984). Resistance to methotrexate due to gene amplification in a patient with acute leukemia.

M. and Pastan, I. (1987). MDR-l gene confers resistance to colchicine, doxorubicin and vinblastine. Proc. Natl. Acad. Sci. USA 84:30043008. 26. Tsuruo, T. (1988). Personal communication. 27. M. and Pastan, I. (1986). Increased vinblastine binding to membrane vesicles from multidrug resistant KB cells. J. BioI. Chern. 261:7921-7928. 28. Pastan, I. (1986). Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150-170 kDa protein detected by photoaffinity labeling. Proc.

Download PDF sample

Rated 4.38 of 5 – based on 50 votes