Modern Techniques for Pathogen Detection by Jürgen Popp, Michael Bauer

By Jürgen Popp, Michael Bauer

This awesome evaluation units a brand new regular for a tools ebook on pathogen detection. the 1st bankruptcy presents an overview of at the moment used regimen equipment, together with their historical past, strengths and weaknesses, in addition to evaluating them to more recent tools. the next chapters then hide novel equipment already in huge use and that are nonetheless extra experimental for regimen purposes.
a useful source for all scientific laboratories and medical associations facing infectious diseases.

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Agents, 36 (Suppl. 2), S6–S16. R. and Masur, H. (2012) Current approaches to the diagnosis of bacterial and fungal bloodstream infections in the intensive care unit. Crit. , 40, 3277–3282. , and Gant, V. (2010) Accurate and rapid identification of bacterial species from positive blood cultures with a DNA-based microarray platform: an observational study. Lancet, 375, 224–230. , and Bouza, E. (2013) Evaluation of MycAssay™ Aspergillus for diagnosis of invasive pulmonary aspergillosis in patients without hematological cancer.

When comparing these results to blood culture, approximately a threefold increase in sensitivity was achieved in a limited cohort of patients [60]. Time-to-result for episodes of bacteremia or “DNAemia” was also reduced, as in other PCR-based approaches, to <8 h despite the additional preanalytic step. However, the full potential of this test, which requires substantial “hands-on-time,” can only be exploited if staffing of the laboratory allows unscheduled access, or automated systems become available [34].

Curr. Opin. Crit. Care, 17, 658–665. , and Wolkewitz, M. (2011) Clinical outcomes of health-careassociated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study. Lancet Infect. , 11, 30–38. , and EPIC II Group of Investigators (2011) Increased mortality associated with methicillin-resistant Staphylococcus aureus (MRSA) infection in the intensive care unit: results from the EPIC II study. Int. J. Antimicrob. Agents, 38, 331–335. , and European Staphylococcal Reference Laboratory Working Group (2010) Geographic distribution of Staphylococcus aureus causing invasive infections in Europe: a References 21.

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