Neurobiology of Epilepsy From Genes to Networks by Elsa Rossignol, Lionel Carmant, Jean-Claude Lacaille

By Elsa Rossignol, Lionel Carmant, Jean-Claude Lacaille

Neurobiology of Epilepsy: From Genes to Networks is the most recent quantity in the growth in mind study series that specializes in new tendencies and advancements. This validated foreign sequence examines significant parts of simple and medical study in the neurosciences, in addition to renowned and rising subfields.

  • Explores new traits and advancements within the neurobiology of Epilepsy
  • Enhances the literature of neuroscience by way of additional increasing the tested, ongoing overseas sequence
  • Progress in mind Research
  • Examines significant components of simple and scientific study in the field

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NeuroImage 16, 32–40. 1073. , 2006. Hemodynamic correlates of epileptiform discharges: an EEG-fMRI study of 63 patients with focal epilepsy. Brain Res. 1088, 148–166. 098. , 1999. Presurgical evaluation of patients with epilepsy and normal MRI: role of scalp video-EEG telemetry. J. Neurol. Neurosurg. Psychiatry 66, 69–71. , 2007. The advantage of combining MEG and EEG: comparison to fMRI in focally stimulated visual cortex. NeuroImage 36, 1225–1235. 2007. 066. , 2005. Application of magnetoencephalography in epilepsy patients with widespread spike or slow-wave activity.

1016/S0013-4694(96)95111-5. , 2005. The hidden causes of surgery-resistant temporal lobe epilepsy: extratemporal or temporal plus? Curr. Opin. Neurol. 18, 125–127. , 1998. Clinical utility of flumazenil-PET versus [18 F]fluorodeoxyglucosePET and MRI in refractory partial epilepsy. A prospective study in 100 patients. Brain J. Neurol. 121 (Pt. 11), 2067–2081. , 2006. Nocturnal frontal lobe epilepsy. Epilepsia 47 (Suppl. 2), 83–86. x. , 2002. Simultaneous EEGcorrelated ictal fMRI. NeuroImage 16, 32–40.

2012a), and O’Roak et al. (2014) Nava et al. (2014a) Torkamani et al. (2014) and EuroEPINOMICS-RES Consortium (2014) Syrbe et al. (2015) Muona et al. (2015) Weckhuysen et al. (2012), Richards et al. (2004), Singh et al. (1998), Singh et al. (2003), Weckhuysen et al. (2013), and Allen et al. (2014) Barcia et al. (2012), Heron et al. (2012), Ishii et al. (2013), and McTague et al. (2013) Lim et al. (2015) and Nakashima et al. (2015) Alazami et al. (2014) 3 Massively parallel sequencing in epilepsy Table 1 Novel Epilepsy Gene Discoveries from 2012 to 2014—cont’d Novel Epilepsy Gene Discoveries Gene Phenotype(s) # Casesa PURA SCN8A EOEE EE, EOEE 15 >30 SLC6A1 SLC13A5 SLC25A22 MAE EOEE NEESBs, MPSI, EME 6 3a 4a SLC35A2 EOEE, IS 8 SNAP25 STX1B EE Fever-associated epilepsy EOEE, OS, IS, DS, EE 1 6 SYNGAP1 EE, ID, ASD >20 TBC1D24 MPSI, DOORS, EOEE, FE + ID, FIME, PME >15 WWOX EOEE, microcephaly 8a STXBP1 >50 References Hunt et al.

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