NINDS at 50: Celebrating 50 Years of Brain Research by Dr. Lewis P. Rowland MD

By Dr. Lewis P. Rowland MD

NINDS has been essentially the most strong cars that pulled and driven the increase of recent neuroscience. This booklet was once written in party of the 50th anniversary of the institute. Its heritage and the historical past of neurology and neuroscience are primarily one. good written, and lavishly followed by means of photos that span the final half-century, this booklet can be a great addition to the library of all people in mind study and the medical neurosciences.

The first part is a background of the Institute, beginning with the allowing laws and targeting the folks who made NINDS a powerhouse of neuroscience study the forged comprises directors, legislators, scientists and certain girls, Mary Lasker and Florence Mahoney. in contrast historical past, the leaders of the intramural application give you the historical past of significant contributions. The a lot greater extramural application encompasses biomedical learn facilities through the usa. NINDS has been an important resource of educating for uncomplicated scientists in neurosciences and the only significant resource in constructing scientific research. within the technique glossy clinical neurology and neurosurgery were created. Oral histories offer human phrases for the heritage.

More than 1/2 the publication is dedicated to biographies of scientists whose contributions earned detailed attractiveness via Lasker Awards or Nobel Prizes. between them are Kety, Louis Sokoloff, Roscoe Brady, Nancy Wexler, Carleton Gajdusek, Stanley Prusiner, Julius Axelrod, Arvid Carlsson, Paul Greengard and Eric Kandel. jointly, their tales offer a heritage of clinical boost.

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He was one of the first to use microelectrodes to study the sensory functions of the cerebral cortex. He elucidated a phenomenon called spreading depression, which became important in understanding normal brain physiology and, also, migraine headache. His laboratory continued to bridge both NIMH and NINDS. He died in 1972. Sanford Palay headed the section of neurocytology, pioneering the use of the electron microscope to study brain ultrastructure. He became the Bullard Professor of Anatomy at Harvard in 1961, and later served as editor of the Journal of Comparative Neurology.

While he had administrative responsibilities, Shy found the time to teach himself about electrolytes, isotopes, electrophysiology, and histology. His broad range of interests even led him to publish a monograph in a field far from muscle disease, the use of radioisotopes to localize brain tumors. Shy’s clinical associates in the new institute held the lowest staff positions, repeating tasks they had already completed as residents in their earlier training programs, because almost all of them had come to NINDB to fulfill their military obligations during the Korean War and thereafter.

Lasker’s resolute partner, Florence Mahoney, moved from Miami to Washington to sustain her own interest in NIH. Starting in 1955, just when Hill took over the committees, the CongressLasker axis acquired an additional asset when James Shannon became Director of NIH. He remained in that office until 1968, the longest term of any NIH Director and probably the most influential; his were the golden years of science at NIH. Under his direction, the scientific research at NIH itself and in the extramural programs ascended to new highs.

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