Ovarian Cancer by Jeffrey M. Trent (auth.), David S. Alberts, Earl A. Surwit

By Jeffrey M. Trent (auth.), David S. Alberts, Earl A. Surwit (eds.)

Where do you start to appear for a up to date, authoritative article at the diag­ nosis or administration of a selected malignancy? The few basic oncology textbooks are mostly old-fashioned. unmarried papers in really good journals are informative yet seldom accomplished; those are extra usually initial reviews on a really constrained variety of sufferers. yes basic journals fre­ quently post stable in-depth studies of melanoma subject matters, and released sym­ posium lectures are usually the easiest overviews on hand. regrettably, those studies and vitamins look sporadically, and the reader can by no means determine while a subject matter of specific curiosity can be coated. melanoma remedy and study is a chain of authoritative volumes which target to fulfill this want. it's an try and identify a serious mass of oncology literature masking nearly all oncology subject matters, revised often to maintain the insurance brand new, simply to be had on a unmarried library shelf or through a unmarried own subscription. now we have approached the matter within the following model. First, via di­ viding the oncology literature into particular subdivisions similar to lung melanoma, genitourinary melanoma, pediatric oncology, and so on. moment, by way of asking eminent gurus in each one of those components to edit a quantity at the particular subject on an annual or biannual foundation. each one subject and tumor sort is roofed in a quantity showing often and predictably, discussing present analysis, staging, markers, all kinds of therapy modalities, simple biology, and more.

Show description

Read or Download Ovarian Cancer PDF

Best cancer books

Cancer: Basic Science and Clinical Aspects

This ahead having a look melanoma biology publication appeals to a panoramic viewers. Introductory chapters that offer the molecular, mobile, and genetic details had to understand the fabric of the following chapters deliver unprepared scholars on top of things for the remainder of the ebook and function an invaluable refresher for people with prior biology heritage.


This consultant is for breast melanoma sufferers, their spouses and kids, and their households, co-workers, and neighbors. the writer hopes to reply to the sensible, lifestyle questions that each breast melanoma sufferer or family member has. The ebook offers info, concepts, suggestions, and suggestion for every thing from that first biopsy to the five-year check-up.

Gastrointestinal Cancer (M.D. Anderson Cancer Care Series)

Gastrointestinal melanoma comprises melanoma of the digestive process - the esophagus, colon, rectum, anus, liver, pancreas, and different digestive organs. Taken as an entire, there are an expected 250,600 new instances within the US. Colon and rectum melanoma is the 3rd top reason for melanoma and melanoma deaths within the US.

Camptothecins in Cancer Therapy (Cancer Drug Discovery and Development)

A severe overview our present knowing of camptothecins, their shortcomings, and of the chances for making improvements to their medical functionality. The authors talk about new camptothecin analog improvement, drug supply matters for optimizing their anticancer job, and their strength use in quite a few diversified cancers.

Extra info for Ovarian Cancer

Example text

10. II. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. ovarian tumors of serous, endometrioid and clear cell types. Am J Clin Path 79: 98-104, 1983. Buick RN, Pullano R, Knapp RC, Urbach GI, Chang PL, Bast RC Jr: Classification of ovarian tumor associated antigens on the basis of distribution on cell populations undergoing differentiation. Proc Amer Assoc Cancer Res 25: 40, (abstr), 1984. Masuho Y, Zalutsky M, Knapp RC, Bast RC Jr: Interaction of monoclonal antibodies with cell surface antigens of human ovarian carcinomas.

CA 125 is associated with coelomic epithelium and amnion during embryonic development [4]. Traces of CA 125 are found in adult tissues derived from coelomic epithelium, including the pleura, peritoneum and pericardium, as well as the epithelial cells lining the fallopian tube, endometrium and endocervix [4]. CA 125 has been detected in endocervical mucus consistent with the physiological secretion of the antigen. Significantly, CA 125 is also associated with more than 80% of non mucinous epithelial ovarian carcinomas [3, 5].

Conclusions Development of the monoclonal technology has permitted the production of a variety of reagents which bind to antigenic determinants associated with epithelial ovarian carcinomas. None is specific for ovarian carcinoma, but several may prove valuable, particularly for monitoring response to treatment. The CA 125 assay may provide a useful marker for monitoring the course of epithelial ovarian cancer and deserves further evaluation in early detection of the disease. A number of monoclonal antibodies recognize carbohydrate determinants associated with high molecular weight mucinlike molecules.

Download PDF sample

Rated 4.35 of 5 – based on 15 votes