Precision Molecular Pathology of Breast Cancer by Ashraf Khan, Ian O. Ellis, Andrew M. Hanby, Ediz F. Cosar,
By Ashraf Khan, Ian O. Ellis, Andrew M. Hanby, Ediz F. Cosar, Emad A. Rakha, Dina Kandil
This quantity offers a finished evaluate of the molecular mechanisms fascinated by precancerous lesions and benign and malignant breast tumors. Given the complicated molecular pathways in breast melanoma biology, the publication simplifies those complicated mechanisms and highlights the sensible matters very important for day-by-day perform. Sections are based to study breast carcinogenesis and the position of familial predisposition and stem cells in initiation and development of breast melanoma. In-depth chapters current morphologic and molecular correlations in precancerous and malignant breast lesions, whereas outlining hugely useful matters which are in perform this day in breast pathology, comparable to overview of estrogen, progesterone receptors, and HER-2.
Written through specialists within the box, Precision Molecular Pathology of Breast Cancer is a beneficial source that covers the present perform of breast pathology and appears into the long run with an emphasis at the molecular foundation of breast cancer.
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Additional info for Precision Molecular Pathology of Breast Cancer
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Two-Dimensional (2D) Cell Line Models Types and Techniques Over the past century, several breast cancer cell lines have been established. These have proven to be valuable experimental tools with many examples of research carried out with breast cancer cell lines leading to the production of new therapies 3 Modelling the Molecular Pathology of Breast Cancer Initiation 41 for patient benefit. Studies have shown that the molecular subtypes of breast cancer outlined by Perou et al.  can be also delineated in panels of breast cancer cell lines.