Steroid Hormone Regulation of the Brain. Proceedings of an by Kjell Fuxe, Jan-Åke Gustafsson, Lennart Wetterberg

By Kjell Fuxe, Jan-Åke Gustafsson, Lennart Wetterberg

Steroid Hormone legislation of the mind specializes in the development of data of the homes of mind steroid receptors and steroid objective nerve cells, together with the activities of gonadal steroids, adrenocortical steroids, and androgenic steroids at the mind.
The choice good points the paintings of authors who've inspiringly performed huge reports at the motion of steroid hormones. The e-book begins with discussions that time out that steroid hormones not just functionality via intracellular steroid receptors, yet almost certainly via steroid membrane activities to boot. reports to aid this declare are offered. As to the motion of steroid hormones on presynaptic transmitter mechanisms, the ebook means that adrenocortical and gonadal steroids can create adjustments in noradrenaline, adrenaline, and dopamine degrees and turnover in the hypothalamus and preoptic sector. the results of catecholestrogens at the mind also are elaborated.
A contribution to this paper stresses that estrogens have antidopaminergic motion within the extrapyramidal process. this concept is pointed out via a chain of behavioral experiments and measurements of the degrees of striatal acetylcholine.
This choice is usually recommended to scientists drawn to learning the impact of hormones at the mind.

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Extra info for Steroid Hormone Regulation of the Brain. Proceedings of an International Symposium Held at the Wenner–Gren Center, Stockholm, 27–28 October 1980

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Effect of estradiol on α-and (3-adrenoreceptor density in medial basal hypothalamus, cerebral cortex and pineal gland of ovariectomized rats. Neurosci. Lett. 17, 73-77. G. H. Mulder (1976). Effects of hypophysectomy, adrenalectomy and corticosterone treatment on uptake and release of putative central neurotransmitters by rat hypothalamic tissue in vitro. Life Sei. 19, 1719-1726. M. McCann (1980). Effect of blockade of dopaminergic receptors on acetylcholine (Ach)-induced alterations of plasma gonadotropin and prolactin (Prl) in conscious ovariectomized rats.

Gustafsson (1978). J. Biol. , 253, 856-865. , J. -Ä. Gustafsson (1979). J. Biol. , 254, 9284-9290. STEROID HORMONE SITES OF ACTION IN THE BRAIN W. E. STUMPF and M. C. 27514, USA ABSTRACT Evidence for the cellular, subcellular and topographical distribution of steroid hormone target sites has been obtained through the use of our dry-mount and thawmount autoradiographic techniques. This historical review documents that the autoradiographic data frequently precede or contradict negative biochemical evi­ dence and serve as a guide for refined biochemical, anatomical, physiological and behavioral studies.

STEROID HORMONE SITES OF ACTION IN THE BRAIN W. E. STUMPF and M. C. 27514, USA ABSTRACT Evidence for the cellular, subcellular and topographical distribution of steroid hormone target sites has been obtained through the use of our dry-mount and thawmount autoradiographic techniques. This historical review documents that the autoradiographic data frequently precede or contradict negative biochemical evi­ dence and serve as a guide for refined biochemical, anatomical, physiological and behavioral studies.

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