The Molecular Biology of Cancer: A Bridge from Bench to

This taking pictures, entire textual content, broadly revised and up to date for its moment version, presents a close evaluate of the molecular mechanisms underpinning the advance of melanoma and its treatment.

“Bench to Bedside”: A key energy of this e-book that units it except basic melanoma biology references is the interweaving of all elements of melanoma biology from the reasons, improvement and analysis via to the therapy and care of melanoma sufferers – crucial for offering a broader view of melanoma and its impact.

The hugely readable presentation of a fancy box, written by way of a world panel of researchers, experts and practitioners, would offer a good textual content for graduate and undergraduate classes within the biology of melanoma, clinical scholars and certified practitioners within the box getting ready for greater tests, and for researchers and academics within the field.

For the instructing of melanoma biology, certain gains were incorporated to facilitate this use: bullet issues in the beginning of every bankruptcy explaining key strategies and debatable parts; each one bankruptcy builds on innovations realized in prior chapters, with a listing of key impressive questions closing within the box, feedback for extra examining, and questions for scholar evaluation. All chapters include textual content containers that offer extra and proper information.

Key highlights are indexed lower than:

An assessment of the melanoma phone and critical new suggestions.
Selected human cancers: lung, breast, colorectal, prostate, renal, dermis, cervix, and hematological malignancies.
Key mobile techniques in melanoma biology together with (a) routinely vital components reminiscent of cellphone cycle regulate, development legislation, oncogenes and tumour suppressors apoptosis, in addition to (b) extra hugely topical parts of apoptosis, telomeres, DNA harm and service, mobile adhesion, angiogenesis, immunity, epigenetics, and the proteasome.
Clinical oncology: In-depth assurance of significant suggestions equivalent to screening, probability of melanoma and prevention, diagnoses, dealing with melanoma sufferers from begin to palliative care and end-of-life pathways.

Chapters highlighting the direct hyperlinks among melanoma study and medical functions.
New assurance on how melanoma medicinal drugs are literally utilized in particular melanoma sufferers, and the way treatments are built and demonstrated.
Systems Biology and leading edge learn parts lined corresponding to RNA interference (RNAi).
Each bankruptcy comprises key issues, bankruptcy summaries, textual content bins, and topical references for additional comprehension and evaluate.
Quotations were utilized in every one bankruptcy to introduce uncomplicated thoughts in an enjoyable manner.

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Extra info for The Molecular Biology of Cancer: A Bridge from Bench to Bedside (2nd Edition)

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